| Verbandsliga Niederrhein 2000/01 |
| 1. | Borussia Wuppertal | 30 | 21 | 9 | 0 | 69:17 | 72 |
| 2. | Sportfreunde Hamborn 07 | 30 | 17 | 3 | 10 | 66:42 | 54 |
| 3. | VfB Speldorf | 30 | 15 | 5 | 10 | 65:37 | 50 |
| 4. | Union Solingen (N) | 30 | 13 | 8 | 9 | 56:41 | 47 |
| 5. | Hülser SV | 30 | 13 | 6 | 11 | 50:42 | 45 |
| 6. | VfL Rhede | 30 | 13 | 5 | 12 | 39:44 | 44 |
| 7. | FC Kray (N) | 30 | 10 | 12 | 8 | 35:32 | 42 |
| 8. | Union Mülheim (N) | 30 | 12 | 6 | 12 | 58:66 | 42 |
| 9. | Union Nettetal (N) | 30 | 11 | 7 | 12 | 61:59 | 40 |
| 10. | TuRU Düsseldorf (N) | 30 | 10 | 7 | 13 | 44:54 | 37 |
| 11. | SV Hilden-Nord | 30 | 10 | 7 | 13 | 48:65 | 37 |
| 12. | Wuppertaler SV II | 30 | 9 | 9 | 12 | 47:49 | 36 |
| 13. | TSV Ronsdorf | 30 | 9 | 9 | 12 | 47:61 | 36 |
| 14. | 1. FC Viersen | 30 | 6 | 10 | 14 | 40:60 | 28 |
| 15. | VfR Neuss | 30 | 7 | 7 | 16 | 32:57 | 28 |
| 16. | SC Schiefbahn | 30 | 7 | 4 | 19 | 35:66 | 25 |
Aus der Oberliga: FC Remscheid, SV Straelen
Aufsteiger: Bayer Wuppertal, VfB Homberg, Viktoria Goch