| Verbandsliga Niederrhein 1980/81 |
| 1. | VfB Bottrop | 30 | 18 | 8 | 4 | 50:29 | 44:16 |
| 2. | 1. FC Mülheim | 30 | 16 | 9 | 5 | 53:24 | 41:19 |
| 3. | Borussia Mönchengladbach A (N) | 30 | 15 | 9 | 6 | 78:42 | 39:21 |
| 4. | VfL Rhede | 30 | 14 | 9 | 7 | 70:50 | 37:23 |
| 5. | VfR Neuss | 30 | 12 | 13 | 5 | 52:32 | 37:23 |
| 6. | Viktoria Goch | 30 | 15 | 6 | 9 | 56:38 | 36:24 |
| 7. | Fortuna Düsseldorf A | 30 | 12 | 9 | 9 | 47:47 | 33:27 |
| 8. | VfB Lohberg | 30 | 9 | 12 | 9 | 49:40 | 30:30 |
| 9. | SSVg Velbert | 30 | 9 | 10 | 11 | 61:51 | 28:32 |
| 10. | VfB Speldorf (N) | 30 | 9 | 10 | 11 | 37:36 | 28:32 |
| 11. | SV Lintfort (N) | 30 | 10 | 8 | 12 | 48:49 | 28:32 |
| 12. | VfL Benrath | 30 | 12 | 4 | 14 | 41:48 | 28:32 |
| 13. | TuS Grevenbroich | 30 | 10 | 7 | 13 | 46:52 | 27:33 |
| 14. | BV 04 Düsseldorf | 30 | 8 | 9 | 13 | 37:49 | 25:35 |
| 15. | VfB Remscheid (A) | 30 | 4 | 7 | 19 | 35:69 | 15:45 |
| 16. | MSV Moers (A) | 30 | 1 | 2 | 27 | 19:123 | 4:56 |
Aus der Oberliga: ASV Wuppertal
Aufsteiger: 1. FC Wülfrath, VfB Langenfeld, VfB Homberg